Galleria mellonellaas a host model to studyAspergillus terreusvirulence and amphotericin B resistance
نویسندگان
چکیده
منابع مشابه
Developing Galleria mellonella as a model host for human pathogens
The number of studies using G. mellonella as a model host for human pathogens has increased significantly in the last few years. Important studies were published from different countries for evaluating the pathogenesis of bacterial and fungal infections and for exploring the host defenses against pathogens. Therefore, standardized conditions for the use of G. melonella larvae need to be establi...
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Candida species are common human fungal pathogens causing a wide range of clinical diseases, ranging from superficial infections to life-threatening systemic disease. Superficial infections include vaginal candidiasis which affects over 75% of women during their lifetime with 5% of women suffering debilitating recurrent infections. Life-threatening systemic Candida disease is the fourth most co...
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Candida spp. are among the most important human fungal pathogens, with infections ranging from relatively benign, superficial manifestation to life-threatening deep-seated candidiasis and disseminated disease. Different mouse models have been developed to recapitulate the different forms of candidiasis and murine models are considered to be the gold standard to study pathogenesis and analyze ef...
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The membrane fluidity of reduced-amphotericin B (AmB)-sensitivity Kluyveromyces lactis mutant strain is higher than that of the wild-type K. lactis strain. After culture of the K. lactis and K. lactis mutant cells in the presence of subinhibitory doses of AmB (10 and 125 mg/liter, respectively), the plasma membranes of both yeast strains also showed a higher fluidity than did those of control c...
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ژورنال
عنوان ژورنال: Virulence
سال: 2015
ISSN: 2150-5594,2150-5608
DOI: 10.1080/21505594.2015.1045183